I'm sure that the author whose gothic novel inspired this webcomic would have been taken aback by this pastiche. After all, in 1931 even H.P. Lovecraft's zany imagination didn't conceive of stories featuring a protagonist who was a troubled young mother with supernatural powers who bore a child out of wedlock and who worked as an auto mechanic. But he would have recognized a lot of the other elements populating this homage.
If you're a fan of the Cthulhu Mythos, this comic is a must-read. And if you're not, you should still check it out.